Bills vs. Jets 2025 Prediction, Odds, Picks - Jan 4

Updated Jan. 4, 2026 2:43 p.m. ET

Data Skrive

The Buffalo Bills (11-5) are big favorites (-12.5) over the New York Jets (3-13). The Jets have dropped four games in a row. The total for this one is set at 39.5 points.

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Bills vs. Jets Odds & Betting Lines

Bills vs Jets Betting Information updated as of January 4, 2026, 2:33 p.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
Bills	-12.5	-108	-112	39.5	-109	-122

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Bills vs. Jets Prediction & Pick

Pick ATS: Bills (-12.5)
Pick OU: Over (39.5)
Prediction: Bills 36 - Jets 13

How to Watch Buffalo vs. New York

Game date: Sunday, January 4, 2026
Time: 4:25 p.m. ET
Venue: Highmark Stadium
Location: Orchard Park, New York
TV:
Live Boxscore: FOX Sports

Bills vs. Jets Recent Matchups

Over their last five meetings, Buffalo has put up four wins against New York.
New York has been outscored by 69 points in its last five tilts against Buffalo.

Buffalo Betting Info

In 16 Buffalo games this season, it has seven wins against the spread.
The Bills have not covered the spread this season (0-2 ATS) when playing as at least 12.5-point favorites.
Buffalo games this year have gone over the total in eight out of 16 opportunities (50%).
The Bills have a 9-5 record in games they played as the moneyline favorite (winning 64.3% of those games).
Based on this contest's moneyline, the Bills' implied win probability is 89.4%.

Bills Stats

Stat	Average (Total)	Rank
Pass yards	214.0 (3,424)	18
Rush yards	156.4 (2,503)	2
Points scored	27.9 (446)	6
Pass yards against	163.4 (2,615)	1
Rush yards against	140.4 (2,246)	29
Points allowed	22.3 (357)	13

Buffalo's Key Players

Offense

Josh Allen has 3,668 passing yards, 25 touchdowns (eighth in the NFL) and 10 interceptions this year. He has completed 69.3% of his attempts, averaging 229.3 yards per game and 8.0 per attempt.
He has also rushed for 579 yards (second on the Bills) and added 14 touchdowns on the ground, while averaging 36.2 rushing yards per game.
James Cook's rushing output this season includes 1,606 yards (first in the NFL) and 12 TDs. He's averaging 100.4 yards per game and 5.2 per attempt (third in the NFL).
He's caught 33 passes (on 40 targets) for 291 receiving yards with two touchdowns. He's averaging 18.2 receiving yards and 2.1 catches per game.
Through 16 games played, Khalil Shakir is averaging 44.9 yards and 4.5 receptions per game to total 719 receiving yards and 72 catches. He's been targeted 95 times, and has four receiving touchdowns.
Dalton Kincaid averages 3.3 receptions and 47.5 yards per game, and has 523 total receiving yards and 36 catches. He's gotten 46 total targets, and has caught five touchdown passes.

Defense

On defense for the Bills, Cole Bishop has put up 85 tackles, 4.0 TFL, two sacks, and three interceptions in 2025.
Greg Rousseau has 46 tackles, 6.0 TFL, and seven sacks this season.
Joey Bosa has put up 29 tackles, 9.0 TFL, and five sacks this year.
This season, Matt Milano has 67 tackles, 7.0 TFL, and 3.5 sacks.

New York Betting Info

New York has put together an 8-8-0 record against the spread this season.
This year, the Jets have two ATS wins in four games as an underdog of 12.5 points or more.
Games involving New York have hit the over on 10 occasions this season.
The Jets have won three, or 21.4%, of the 14 games they've played as underdogs this season.
Sportsbooks have implied with the moneyline set for this matchup that the Jets have a 14.8% chance to win.

Jets Stats

Stat	Average (Total)	Rank
Pass yards	145.8 (2,332)	32
Rush yards	126.7 (2,027)	7
Points scored	18.3 (292)	28
Pass yards against	213.4 (3,415)	16
Rush yards against	135.0 (2,160)	27
Points allowed	29.3 (468)	30

New York's Key Players

Offense

Breece Hall has rushed for four touchdowns this year, and has racked up 1,065 total rushing yards (66.6 per game and 4.4 per carry).
On top of his rushing statistics, Hall has caught 36 passes (on 48 targets) for 350 yards (fourth on the Jets), with one receiving touchdown. He's averaging 21.9 yards per game.
In six games, Tyrod Taylor has 779 passing yards, with five touchdowns against five interceptions and completing 59.7% of his attempts.
Taylor also has one rushing touchdown and 143 rushing yards (fourth on the Jets).
In 15 games played this season, Adonai Mitchell has 33 catches (2.2 receptions per game on 4.7 targets per game) for 453 yards and two receiving touchdowns.
John Metchie has been targeted 44 times, resulting in 30 catches for 254 yards .

Defense

In 2025, Jamien Sherwood has put up 2.0 sacks to go with 8.0 TFL and 147 tackles through 16 games.
Quincy Williams has 79 tackles, 8.0 TFL, 3.5 sacks, and six passes defended.
Malachi Moore has 86 tackles and 3.0 TFL in the 2025 season. He is second on the Jets in tackles.
Brandon Stephens has 4.0 TFL and 72 tackles over 16 games.