Data Skrive
The San Francisco 49ers (6-10) will be trying to end a three-game losing streak against the Arizona Cardinals (7-9). The Cardinals are the favorites, expected to win by at least a field goal but less than a touchdown (currently -5.5). The expected point total for the matchup is set at 42.5.
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Cardinals vs. 49ers Odds & Betting Lines
| Favorite | Spread | Favorite Spread Odds | Underdog Spread Odds | Total | Over Total Odds | Under Total Odds |
|---|---|---|---|---|---|---|
| Cardinals | -5.5 | -110 | -121 | 42.5 | -110 | -110 |
Cardinals vs. 49ers Prediction & Pick
- Pick ATS: Cardinals (-5.5)
- Pick OU: Over (42.5)
- Prediction: Cardinals 26 - 49ers 20
How to Watch Arizona vs. San Francisco
- Game Date: Sunday, January 5, 2025
- Time: 4:25 p.m. ET
- Venue: State Farm Stadium
- Location: Glendale, Arizona
- TV: Watch on FOX
- Live Boxscore: FOX Sports
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Cardinals vs. 49ers Recent Matchups
- Over their last five meetings, San Francisco has put up four wins against Arizona.
- Arizona has been outpaced by 87 points in its last five tilts versus San Francisco.
Arizona Betting Info
- Arizona has 10 wins in 16 games versus the spread this year.
- The Cardinals have covered the spread once this season (1-1 ATS) when playing as at least 5.5-point favorites.
- Arizona has combined with its opponent to hit the over in 43.8% of its contests this year (seven times over 16 games with a set point total).
- When playing as moneyline favorites, the Cardinals are 2-4 (winning 33.3% of the time).
- The Cardinals have a 66.4% chance to win this contest, based on the implied probability of the moneyline.
Cardinals Stats
| Stat | Average (Total) | Rank |
|---|---|---|
| Pass yards | 212.3 (3,397) | 18 |
| Rush yards | 143.8 (2,300) | 7 |
| Points scored | 22.1 (353) | 15 |
| Pass yards against | 211 (3,376) | 12 |
| Rush yards against | 125.7 (2,011) | 20 |
| Points allowed | 22.2 (355) | 14 |
Arizona's Key Players
Offense
- Kyler Murray has 3,609 passing yards in 16 games this year, averaging 225.6 per game with a 68.6% completion percentage and 17 touchdowns against 11 interceptions.
- He has also rushed for 550 yards (second on the Cardinals) and added five touchdowns on the ground, while averaging 34.4 rushing yards per game.
- Marvin Harrison Jr. has 57 catches for 822 yards and seven TDs. In 16 games, he is averaging 3.6 catches and 51.4 yards per game.
- In the passing attack, Trey McBride, has totaled 1,081 receiving yards and one touchdown after grabbing 104 balls (fourth in the NFL) on 136 targets. Per game, he's averaging 72.1 yards and 6.9 receptions in 15 games.
- Michael Wilson has racked up 548 receiving yards and four touchdowns with 47 catches on 71 targets. He is averaging 2.9 receptions and 34.3 yards per game.
Defense
- Over on defense, Budda Baker has 154 tackles, 9.0 TFL, two sacks, and five passes defended in 2024.
- Kyzir White has intercepted one pass and added 127 tackles, 8.0 TFL, 2.5 sacks, and two passes defended.
- Mack Wilson has collected 73 tackles, 4.0 TFL, three sacks, and one interception this year.
- So far this season, Jalen Thompson has 88 tackles and 2.0 TFL.
San Francisco Betting Info
- San Francisco has covered the spread five times this season (5-11-0).
- The 49ers have been underdogs by 5.5 points or more two times this year and have not covered the spread once.
- San Francisco games have gone over the total nine times this season.
- The 49ers have been the underdog in three games this season, and they have failed to win any of those contests.
- The moneyline for this contest implies a 37.9% chance of a victory for the 49ers.
49ers Stats
| Stat | Average (Total) | Rank |
|---|---|---|
| Pass yards | 246 (3,936) | 4 |
| Rush yards | 126.6 (2,025) | 11 |
| Points scored | 22.8 (365) | 14 |
| Pass yards against | 189.8 (3,036) | 4 |
| Rush yards against | 122.9 (1,967) | 17 |
| Points allowed | 24.3 (389) | 22 |
San Francisco's Key Players
Offense
- Brock Purdy is averaging 8.5 passing yards per attempt (third in the NFL) and 257.6 yards per game this year, completing 65.9% of his passes on the way to 3,864 total yards (eighth in the NFL), 20 touchdowns and 12 interceptions through 15 games.
- He's added 323 yards on the ground (third on the 49ers), with five rushing touchdowns. He's averaging 21.5 yards per game and 4.9 per attempt.
- George Kittle has 76 catches for 1,079 yards and eight receiving touchdowns. He has been targeted 91 times and averages 5.4 receptions per game in 14 games played.
- Jauan Jennings has recorded 923 receiving yards and six touchdowns on 70 receptions, while being targeted 103 times this season.
- Deebo Samuel has 51 catches for 670 yards and three receiving touchdowns. He averages 3.4 yards per game in 15 games and has been targeted 81 times.
Defense
- Fred Warner has amassed 1.0 sack to go with 4.0 TFL, 123 tackles, and two interceptions over 16 games in 2024.
- Nick Bosa has totaled 9.0 sacks in addition to his 15.0 TFL, 52 tackles, and one interception through 13 games.
- During the 2024 season, Deommodore Lenoir has 85 tackles, 2.0 TFL, and two interceptions in 15 games.
- Leonard Floyd has 39 tackles, 8.0 TFL, 8.5 sacks, and one pass defended.
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
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