Cardinals vs. Panthers 2024 Prediction, Odds, Picks - Dec 22

Updated Dec. 22, 2024 12:43 p.m. ET

Data Skrive

The Arizona Cardinals (7-7) are the favorites, expected to win by at least a field goal but less than a touchdown (currently -5.5) over the Carolina Panthers (3-11). The Panthers have lost four games straight. The total for this one is set at 47 points.

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Cardinals vs. Panthers Odds & Betting Lines

Cardinals vs Panthers Betting Information updated as of December 22, 2024, 11:33 a.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
Cardinals	-5.5	-110	-110	47	-108	-112

Cardinals vs. Panthers Prediction & Pick

Pick ATS: Cardinals (-5.5)
Pick OU: Under (47)
Prediction: Cardinals 30 - Panthers 16

How to Watch Arizona vs. Carolina

Game Date: Sunday, December 22, 2024
Time: 1 p.m. ET
Venue: Bank of America Stadium
Location: Charlotte, North Carolina
TV: Watch on FOX
Live Boxscore: FOX Sports

Cardinals vs. Panthers Recent Matchups

In their past five head-to-head contests, Carolina has won against Arizona four times.
Over their last five head-to-head matchups, Carolina has put up 167 points, while Arizona has accumulated 91.

Arizona Betting Info

Arizona has played 14 games, posting nine wins against the spread.
The Cardinals have been favored by 5.5 points or more once this season, and covered the spread.
Arizona games this year have gone over the total in six out of 14 opportunities (42.9%).
When playing as the moneyline favorite, the Cardinals are 2-3 (winning 40% of the time).
Based on this contest's moneyline, the Cardinals' implied win probability is 71.0%.

Cardinals Stats

Stat	Average (Total)	Rank
Pass yards	209.9 (2,938)	21
Rush yards	141.5 (1,981)	7
Points scored	22.4 (314)	16
Pass yards against	217 (3,038)	17
Rush yards against	121.4 (1,700)	18
Points allowed	21.9 (306)	10

Arizona's Key Players

Offense

Kyler Murray has 3,086 passing yards, 15 touchdowns and eight interceptions this year. He has completed 69% of his attempts, averaging 220.4 yards per game and 7.2 per attempt.
He has also rushed for 455 yards (second on the Cardinals) and added four touchdowns on the ground, while averaging 32.5 rushing yards per game.
James Conner has recorded 973 rushing yards (10th in the NFL) with seven touchdowns (69.5 yards per game over 14 games). His 4.5 yards per attempt rank 18th in the NFL.
He has caught 41 passes (on 48 targets) for 361 receiving yards with one touchdown. He's averaging 25.8 receiving yards and 2.9 catches per game.
Marvin Harrison Jr. has seven touchdown catches this season, and has 47 catches for 687 yards on 92 targets, while averaging 3.4 catches and 49.1 yards per game.
Trey McBride averages 6.8 receptions and 72.2 yards per game, and has 938 total receiving yards and 89 catches (sixth in the NFL). He's gotten 116 total targets, but has not caught a touchdown pass.

Defense

On the defensive side, Budda Baker has 141 tackles, nine TFL, and two sacks in 2024. His tackle total leads the Cardinals and is second in the NFL.
Kyzir White has picked off one pass and added 111 tackles, six TFL, 1.5 sacks, and two passes defended.
Mack Wilson has collected one interception and has added 67 tackles, four TFL, three sacks, and four passes defended.
Jalen Thompson has two TFL and 72 tackles this year.

Carolina Betting Info

Carolina is 6-8-0 against the spread this season.
So far this year, the Panthers have been installed as underdogs by a 5.5-point margin or more 10 times and are 6-4 ATS in those matchups.
Games involving Carolina have hit the over on 10 occasions this season.
The Panthers have won three, or 23.1%, of the 13 games they've played as underdogs this season.
The Panthers have a 33.3% chance to win this game based on the implied probability of the moneyline.

Panthers Stats

Stat	Average (Total)	Rank
Pass yards	186 (2,604)	29
Rush yards	102.9 (1,441)	24
Points scored	17.6 (247)	28
Pass yards against	213.2 (2,985)	11
Rush yards against	173 (2,422)	32
Points allowed	29.9 (418)	32

Carolina's Key Players

Offense

Chuba Hubbard has rushed for eight touchdowns this year, and has put up 1,043 total rushing yards (74.5 per game and 4.6 per carry).
On top of his impact in the run game, Hubbard has caught 39 passes (on 49 targets) for 158 yards (seventh on the Panthers), with one receiving touchdown. He's averaging 11.3 yards per game.
Bryce Young has 1,791 passing yards, eight touchdowns and nine interceptions. His completion percentage is 59.8% and he averages 162.8 yards per game and 6.1 per attempt.
He has added 149 rushing yards (second on the Panthers), with three touchdowns on the ground (averaging 13.5 yards per game and 4.8 per carry).
Through 13 games played this season, Xavier Legette has 41 catches (3.2 receptions per game on 5.4 targets per game) for 439 yards and four receiving touchdowns.
In six games, Andy Dalton has 989 passing yards, with seven touchdowns against six interceptions and completing 66.3% of his attempts.

Defense

So far in 2024, Josey Jewell has 3.5 sacks to go with seven TFL, 91 tackles, and one interception through 11 games.
Xavier Woods has two TFL, 96 tackles, and three interceptions over 14 games.
Jaycee Horn has two sacks (fifth on the Panthers) in addition to his five TFL, 64 tackles, and one interception.
A'Shawn Robinson has put up 4.5 sacks (first on the Panthers) to go with seven TFL and 66 tackles through 13 games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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