Chiefs' Isiah Pacheco, Rams' Cooper Kupp among best bets to score in Week 6 of NFL season

Updated Oct. 11, 2023 1:31 p.m. ET

Associated Press

Cooler temperatures are coming, but these players are ever productive in any weather. Here are my best bets to score in Week 6.

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Running Back

ISIAH PACHECO, CHIEFS

Pacheco has scored in three consecutive games, and he’s set to keep the trend going this week against a Broncos team that’s our No. 1 matchup for opposing running backs. Just last week, they got dominated by the Jets' Breece Hall to the tune of 194 total yards and a score. With a TD dependency of 29.8% and an ever-increasing snap count, Pacheco is expected to find the end zone this week at least once.

KYREN WILLIAMS, RAMS

Perhaps the most surprising running back in the top five in scoring this season — six TDs, Williams has run away with the starting gig in LA. He could continue his streak of success this week when the Rams face the Cardinals, our sixth-best matchup for opposing runners going into Week 6. Tied with Josh Jacobs for the highest snap count for a running back this season (84%), Williams rarely leaves the field, and he’s likely to be the top goal-line option for a Rams offense that has been productive, even before Cooper Kupp returned. Williams has -125 odds to score this week, the best odds for a running back.

RAHEEM MOSTERT, DOLPHINS

Unfortunately for the Dolphins, they’ve lost rookie phenom De’Von Achane for multiple weeks to a knee injury. Fortunately, they have Mostert. The speedy vet has eight TDs this season. Carolina is a favorable matchup for running backs, our second-best matchup. Mostert comes into the game with -125 odds to hit the end zone, and his 60% snap count is sure to increase now that Achane is unavailable. Jeff Wilson Jr. may join the backfield starting this week, but Mostert is still the lead back in Miami.

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Wide Receiver

JA’MARR CHASE, BENGALS

Chase was scoreless for his first four games this season. However he had three TDs in Week 5, and he’s primed to keep up the good work in Week 6 against Seattle. The Seahawks are our second-best matchup for opposing wide receivers, allowing the third-most fantasy points per game (30.2) so far this season. Tee Higgins may miss another game, enabling Chase even more target share. With a 93% snap count and -105 odds on behalf of Vegas, Chase is one of our best bets to score this week.

COOPER KUPP, RAMS

Kupp didn’t miss a step in his first game this season in Week 5, catching eight passes for 118 yards, but he was missing one thing and it won’t elude him this week. Kupp could score against a Cardinals team that’s our sixth-best matchup for opposing wide receivers and third-best matchup for opposing QBs. Kupp scored seven times in only nine games last season.

CEEDEE LAMB, COWBOYS

Lamb has had a slow season of sorts, having scored only once as we enter Week 6. Dallas’ dominant defense has made the offense a luxury at times so he hasn’t always been a necessary playmaker. That is unlikely to be the case this week, as the Cowboys face the Chargers in what could be a shootout. As proficient as LA is through the air offensively, they are as deficient in defending the pass, so much so that they’re our best matchup for opposing WRs, allowing a league-high 32.6 fantasy points per game average. Lamb and Co. could exploit this advantage this week, putting Lamb in position to score at least once. Set him and sleep easy.

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This column was provided to The Associated Press by RosterWatch, www.rosterwatch.com.