The Biggest NFL Upsets in Week 16 - 2024

Updated Dec. 24, 2024 6:34 p.m. ET

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You want upsets? We've got upsets. Multiple underdogs defeated the favorite in Week 16 of the 2024 NFL season. Keep reading to find a complete list of the teams that beat the odds.

Read more about last week's NFL games on FOX Sports!

NFL Week 16's Biggest Upsets

Panthers 36, Cardinals 30

• Spread: Cardinals -5
• Total: Over (47)
• Moneyline: Cardinals -250, Panthers +200

Cowboys 26, Buccaneers 24

• Spread: Buccaneers -4
• Total: Over (47.5)
• Moneyline: Buccaneers -210, Cowboys +170

Commanders 36, Eagles 33

• Spread: Eagles -4
• Total: Over (47)
• Moneyline: Eagles -225, Commanders +185

Dolphins 29, 49ers 17

• Spread: 49ers -1.5
• Total: Over (44.5)
• Moneyline: 49ers -125, Dolphins +105

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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