Lyon and Eintracht Frankfurt secured first-leg victories Wednesday in the Europa League round of 16.
In Spain, all the goals came in the opening 32 minutes as Frankfurt won 2-1 at Real Betis.
Filip Kostić scored the opener for the German side in the 14th by shooting over goalkeeper Claudio Bravo. It was canceled out by Nabil Fekir curling in a shot on the half-hour but Daichi Kamada slotted Frankfurt back in front two minutes later from close range.
Bravo prevented the visitors from taking a bigger advantage back to Germany for next week's second leg by saving a penalty in the second half from Rafael Borré.
In Portugal, Lucas Paquetá was set up by Moussa Dembele’s pass in the 59th minute to clinch Lyon’s 1-0 win at Porto.
The remaining last-16 first legs are on Thursday, including Barcelona hosting Galatasaray.
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