Michigan vs. Iowa State Prediction, Odds, Picks – Women's Basketball NCAA Tournament First Round 2025

Updated Mar. 21, 2025 8:05 a.m. ET

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An opening-round NCAA Tournament matchup will see the 6-seed Michigan Wolverines (22-10) play as a 2.5-point favorite against the No. 11 seed Iowa State Cyclones (23-11) on Friday at Purcell Pavilion. The matchup tips off at 11:30 a.m. ET on ESPN2. Here's a look into this 6-11 matchup before filling out your brackets. The matchup has an over/under set at 149.5 points.

NCAAW BK

NCAA TOURNMENT - FIRST ROUND

Michigan Wolverines MICH

80

FINAL

74

6

Michigan ^23-10

MICH ^23-10

80

11

Iowa State ^23-12

ISU ^23-12

74

Iowa State Cyclones ISU

FINAL

MICH -5.5 OVER 149.5

Michigan vs. Iowa State Game Info

• Game day: Friday, March 21, 2025
• Game time: 11:30 a.m. ET
• TV channel: ESPN2
• Follow this game live on FOX Sports

Michigan vs. Iowa State Odds

Michigan vs. Iowa State Prediction

• Computer Pick ATS: Iowa State (+2.5)
  
• Computer Pick OU: Under (149.5)
  
• Computer Prediction: Michigan 73, Iowa State 71

Learn more about the Michigan Wolverines vs. the Iowa State Cyclones game on FOX Sports!

Michigan Betting Insights

• The Wolverines' record against the spread is 12-12-0.
• Michigan is 6-7 ATS as 2.5-point favorites or more.
• This season, 12 of the Wolverines' 24 games have hit the over.
• This season, Michigan has won nine out of the 12 games, or 75%, in which it has been the moneyline favorite.
• The Wolverines have a record of 9-3 in games where bookmakers favor them by at least -142 on the moneyline.

Iowa State Betting Insights

• The Cyclones' record against the spread is 10-17-0.
• Iowa State has an ATS record of 3-6 as a 2.5-point underdog or more.
• This year, 16 of the Cyclones' 27 games have hit the over.
• Iowa State has won in one of the 10 contests it has been named as the moneyline underdog this year.
• This year, the Cyclones have won one of nine games when listed as at least +120 or worse on the moneyline.

FINAL

ISU 74 · MICH 80

WOMEN'S NCAA BK

SPREAD

TO WIN

TOTAL

11

Iowa State Cyclones

ISU

+5.5

+171

O 149.5

6

Michigan Wolverines

MICH

-5.5

-206

U 149.5

Michigan's Top Performers

Iowa State's Top Performers

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Michigan Wolverines

Iowa State Cyclones

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Michigan Wolverines

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WCBK - Iowa State Cyclones vs. Michigan Wolverines - 03/21/2025

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