College Football

Iowa State vs. Houston Prediction, Odds, Expert Pick

Updated Sep. 26, 2024 4:16 p.m. ET

The Houston Cougars (1-3) are 14.5-point underdogs in a home Big 12 matchup against the No. 18 Iowa State Cyclones (3-0) on Saturday, September 28, 2024 at John O'Quinn Field at TDECU Stadium. The total has been set at 43.5 points for this matchup.

Last time around, the Cyclones defeated the Arkansas State Red Wolves, with 52-7 being the final score. Last time out, the Cougars fell to the Cincinnati Bearcats, with 34-0 being the final score.

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Iowa State vs. Houston Game Information & Odds

When: Saturday, September 28, 2024 at 7:00 p.m. ET
Location: John O'Quinn Field at TDECU Stadium in Houston, Texas
TV: Fox Sports 1
Live Box Score on FOX Sports

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Iowa State vs Houston Betting Information updated as of September 26, 2024, 2:47 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Iowa State	-14.5 (-109)	-667	+464	43.5	-109	-111

Iowa State vs. Houston Prediction

Pick ATS: Houston (+14.5)
Pick OU: Under (43.5)
Prediction: Iowa State 24, Houston 17

Predictions are made by the Data Skrive betting model.

Learn more about the Iowa State Cyclones vs. the Houston Cougars game on FOX Sports!

Pick by FOX Sports Betting Analyst Chris Fallica:

The Cyclones put up their best offensive performance of the young season last week, running and passing for over 230 each in a 52-7 rout of Arkansas State. This was the same Arkansas State that lost 28-18 at Michigan the week before. Still, Houston’s defense hasn’t been terrible this year, and off a shutout loss at Cincinnati, I’d expect this Willie Fritz team to put up a bit more of a fight.

PICK: Houston (+14.5) to lose by fewer than 14.5 points, or win outright

Iowa State vs. Houston Betting Insights

Per the spread and over/under, the implied score for the matchup is Cyclones 29, Cougars 14.
The Cyclones have an 87.0% chance to win this game per the moneyline's implied probability. The Cougars have a 17.7% implied probability.
Iowa State has covered twice in two games with a spread this season.
Houston has covered twice in four games with a spread this season.

Iowa State vs. Houston: 2024 Stats Comparison

	Iowa State	Houston
Off. Points per Game (Rank)	31 (91)	13 (127)
Def. Points per Game (Rank)	9.7 (8)	21 (72)
Turnovers Allowed (Rank)	3 (26)	7 (103)
Turnovers Forced (Rank)	7 (23)	4 (73)

Iowa State 2024 Key Players

Name	Position	Stats
Rocco Becht	QB	743 YDS (68.4%) / 6 TD / 2 INT 18 RUSH YDS / 2 RUSH TD / 6 RUSH YPG
Jaylin Noel	WR	15 REC / 317 YDS / 2 TD / 105.7 YPG
Jayden Higgins	WR	17 REC / 208 YDS / 3 TD / 69.3 YPG
Carson Hansen	RB	80 YDS / 2 TD / 26.7 YPG / 4.7 YPC
Malik Verdon	DB	22 TKL / 2 TFL / 1 INT / 1 PD
Beau Freyler	DB	20 TKL / 1 TFL / 1 INT / 1 PD
Kooper Ebel	LB	16 TKL / 1 TFL / 1 SACK
J.R. Singleton	DL	9 TKL / 2 TFL / 2 SACK

Houston 2024 Key Players

Name	Position	Stats
Donovan Smith	QB	610 YDS (65.3%) / 2 TD / 4 INT 43 RUSH YDS / 2 RUSH TD / 10.8 RUSH YPG
Joseph Manjack IV	WR	10 REC / 146 YDS / 2 TD / 36.5 YPG
Re'Shaun Sanford II	RB	166 YDS / 0 TD / 41.5 YPG / 5.2 YPC 8 REC / 96 REC YDS / 0 REC TD / 24 REC YPG
Stacy Sneed	RB	138 YDS / 1 TD / 34.5 YPG / 5.3 YPC
Michael Batton	LB	28 TKL / 3 TFL / 2 SACK
Keith Cooper Jr.	DL	14 TKL / 4 TFL / 2 SACK
A.J. Haulcy	DB	21 TKL / 0 TFL / 1 INT / 1 PD
Hershey McLaurin	DB	16 TKL / 2 TFL