College Football

Iowa vs. Iowa State odds: How to bet, picks, more

Published Sep. 11, 2021 1:23 a.m. ET

Week 2 of the 2021 college football season features a battle of the heartland – and one that happens to pit two of the nation's top 10 teams against each other.

Here are the odds, point spreads, moneylines, total scoring over/under and picks you need to make your bets on the Iowa Hawkeyes versus the Iowa State Cyclones at FOX Bet.

No. 10 Iowa at No. 9 Iowa State (Saturday, 4:30 p.m. ET, ABC)
Point spread: Iowa State -4 (Iowa State favored to win by more than 4.5 points, otherwise Iowa covers)
Moneyline: Iowa State -213 favorites to win outright (bet $10 to win $14.69 total); Iowa +175 underdogs to win outright (bet $10 to win $18.50 total)
Total scoring over/under: 46.5 points scored by both teams combined

Expert analysis via FOX Sports Betting Analyst Sam Panayotovich: "The Cyclones didn’t show much against Northern Iowa, so we’re getting a really good number here against an Iowa squad that steamrollered Indiana 34-6.

"Go figure, the Hawkeyes morphed from the unwanted favorite to the public underdog in just one week, and that’s always a cause for concern.

"I’ll take Matt Campbell and Brock Purdy in a big game any day."

PICK: Iowa State (-4) to win by more than 4 points at FOX Bet

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