National Football League

2023 NFL Week 13 odds, predictions: Picks, lines, spreads for every game

Updated Nov. 28, 2023 5:11 p.m. ET

It will be a revenge game for the San Francisco 49ers (8-3) when they play at the Philadelphia Eagles (10-1) in a battle of NFL division leaders on Sunday.

The Eagles beat the 49ers 31-7 in last season's NFC Championship Game as Philadelphia advanced to Super Bowl LVII.

The 49ers-Eagles rematch is at 4:25 p.m. ET Sunday and can be seen on FOX and the FOX Sports App

Here's everything you need to know about the NFL odds for Week 13 — the point spread, moneyline and total Over/Under.

All times ET

BYES: Bears, Bills, Giants, Ravens, Raiders, Vikings

THURSDAY'S GAME

Seahawks @ Cowboys (8:15 p.m., Amazon Prime Video)

Point spread: Cowboys -8.5 (Cowboys favored to win by more than 8.5 points, otherwise Seahawks cover)
Moneyline: Cowboys -406 favorites to win (bet $10 to win $12.46 total); Seahawks +315 underdogs to win (bet $10 to win $41.50 total)
Total scoring Over/Under: 46 points scored by both teams combined

Eagles stage comeback to defeat Bills in OT | The Carton Show

SUNDAY'S GAMES

Lions @ Saints (1 p.m., FOX and FOX Sports App)

Point spread: Lions -3.5 (Lions favored to win by more than 3.5 points, otherwise Saints cover)
Moneyline: Lions -185 favorites to win (bet $10 to win $15.41 total); Saints +155 underdogs to win (bet $10 to win $25.50 total)
Total scoring Over/Under: 45 points scored by both teams combined

Falcons @ Jets (1 p.m., FOX and FOX Sports App)

Point spread: Falcons -3 (Falcons favored to win by more than 3 points, otherwise Jets cover)
Moneyline: Falcons -142 favorites to win (bet $10 to win $17.04 total); Jets +120 underdogs to win (bet $10 to win $22 total)
Total scoring Over/Under: 34 points scored by both teams combined

Dolphins @ Commanders (1 p.m., FOX and FOX Sports App)

Point spread: Dolphins -9.5 (Dolphins favored to win by more than 9.5 points, otherwise Commanders cover)
Moneyline: Dolphins -456 favorites to win (bet $10 to win $12.19 total); Commanders +347 underdogs to win (bet $10 to win $44.70 total)
Total scoring Over/Under: 50 points scored by both teams combined

Washington Commanders

WAS

Colts @ Titans (1 p.m., CBS)

Point spread: Colts -2 (Colts favored to win by more than 2 points, otherwise Titans cover)
Moneyline: Colts -130 favorites to win (bet $10 to win $17.69 total); Titans +110 underdogs to win (bet $10 to win $21 total)
Total scoring Over/Under: 42 points scored by both teams combined

Chargers @ Patriots (1 p.m., CBS)

Point spread: Chargers -5.5 (Chargers favored to win by more than 5.5 points, otherwise Patriots cover)
Moneyline: Chargers -243 favorites to win (bet $10 to win $14.12 total); Patriots +198 underdogs to win (bet $10 to win $29.80 total)
Total scoring Over/Under: 41 points scored by both teams combined

Cardinals @ Steelers (1 p.m., CBS)

Point spread: Steelers -5.5 (Steelers favored to win by more than 5.5 points, otherwise Cardinals cover)
Moneyline: Steelers -250 favorites to win (bet $10 to win $14 total); Cardinals +203 underdogs to win (bet $10 to win $30.30 total)
Total scoring Over/Under: 40 points scored by both teams combined

Broncos @ Texans (1 p.m., CBS)

Point spread: Texans -3 (Texans favored to win by more than 3 points, otherwise Broncos cover)
Moneyline: Texans -158 favorites to win (bet $10 to win $16.33 total); Broncos +133 underdogs to win (bet $10 to win $23.30 total)
Total scoring Over/Under: 45.5 points scored by both teams combined

Panthers @ Buccaneers (4:05 p.m., CBS)

Point spread: Buccaneers -6 (Buccaneers favored to win by more than 6 points, otherwise Panthers cover)
Moneyline: Buccaneers -264 favorites to win (bet $10 to win $13.79 total); Panthers +213 underdogs to win (bet $10 to win $31.30 total)
Total scoring Over/Under: 37.5 points scored by both teams combined

Browns @ Rams (4:25 p.m., FOX and FOX Sports App)

Point spread: Rams -4.5 (Rams favored to win by more than 4.5 points, otherwise Browns cover)
Moneyline: Rams -211 favorites to win (bet $10 to win $14.74 total); Browns +174 underdogs to win (bet $10 to win $27.40 total)
Total scoring Over/Under: 38.5 points scored by both teams combined

49ers @ Eagles (4:25 p.m., FOX and FOX Sports App)

Point spread: 49ers -2.5 (49ers favored to win by more than 2.5 points, otherwise Eagles cover)
Moneyline: 49ers -146 favorites to win (bet $10 to win $16.85 total); Eagles +123 underdogs to win (bet $10 to win $22.30 total)
Total scoring Over/Under: 46.5 points scored by both teams combined

Chiefs at Packers (8:20 p.m., NBC)

Point spread: Chiefs -6.5 (Chiefs favored to win by more than 6.5 points, otherwise Packers cover)
Moneyline: Chiefs -298 favorites to win (bet $10 to win $13.36 total); Packers +237 underdogs to win (bet $10 to win $33.70 total)
Total scoring Over/Under: 42.5 points scored by both teams combined

MONDAY'S GAME

Bengals @ Jaguars (8:15 p.m. ET, ESPN/ABC)

Point spread: Jaguars -8 (Jaguars favored to win by more than 8 points, otherwise Bengals cover)
Moneyline: Jaguars -391 favorites to win (bet $10 to win $12.56 total); Bengals +304 underdogs to win (bet $10 to win $40.40 total)
Total scoring Over/Under: 39 points scored by both teams combined