National Football League

2024 NFL Week 2 odds, lines, spreads for all 16 games

Updated Sep. 21, 2024 12:24 p.m. ET

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And just like that, Week 2 of the NFL season is here.

Let's check out the lines for each NFL game at DraftKings Sportsbook, as the second week of the season is upon us. 

(All times ET)

2024 NFL Week 2 Odds

THURSDAY, SEPT. 12

BUFFALO BILLS @ MIAMI DOLPHINS 

Point spread: Dolphins -1 (Dolphins favored to win by one point or more, otherwise Bills cover)
Moneyline: Dolphins -118 favorites to win (bet $10 to win $18.47 total); Bills -102 underdogs to win (bet $10 to win $19.80 total)
Total scoring Over/Under: 51 points scored by both teams combined

SUNDAY, SEPT. 15

NEW ORLEANS SAINTS @ DALLAS COWBOYS (1 p.m., FOX and FOX Sports app)

Point spread: Cowboys -6.5 (Cowboys favored to win by more than 6.5 points, otherwise Saints cover)
Moneyline: Cowboys -290 favorites to win (bet $10 to win $13.45 total); Saints +235 underdogs to win (bet $10 to win $33.50 total)
Total scoring Over/Under: 47 points scored by both teams combined

FINAL

NO 44 · DAL 19

NFL

SPREAD

TO WIN

TOTAL

New Orleans Saints

NO

+6.5

+240

O 47

Dallas Cowboys

DAL

-6.5

-299

U 47

TAMPA BAY BUCCANEERS @ DETROIT LIONS (1 p.m., FOX and FOX Sports app)

Point spread: Lions -7.5 (Lions favored to win by more than 7.5 points, otherwise Buccaneers cover)
Moneyline: Lions -375 favorites to win (bet $10 to win $12.67 total); Buccaneers +295 underdogs to win (bet $10 to win $39.50 total)
Total scoring Over/Under: 51.5 points scored by both teams combined

FINAL

TB 20 · DET 16

NFL

SPREAD

TO WIN

TOTAL

Tampa Bay Buccaneers

TB

+7.5

+288

O 51.5

Detroit Lions

DET

-7.5

-377

U 51.5

INDIANAPOLIS COLTS @ GREEN BAY PACKERS (1 p.m., FOX and FOX Sports app)

Point spread: Colts -3 (Colts favored to win by more than 3 points, otherwise Packers cover)
Moneyline: Colts -142 favorites to win (bet $10 to win $17.04 total); Packers +120 underdogs to win (bet $10 to win $22 total)
Total scoring Over/Under: 41.5 points scored by both teams combined

FINAL

IND 10 · GB 16

NFL

SPREAD

TO WIN

TOTAL

Indianapolis Colts

IND

-2.5

-139

O 41.5

Green Bay Packers

GB

+2.5

+118

U 41.5

NEW YORK JETS @ TENNESSEE TITANS (1 p.m., CBS)

Point spread: Jets -4 (Jets favored to win by more than 4 points, otherwise Titans cover)
Moneyline: Jets -185 favorites to win (bet $10 to win $15.41 total); Titans +154 underdogs to win (bet $10 to win $25.40 total)
Total scoring Over/Under: 40.5 points scored by both teams combined

FINAL

NYJ 24 · TEN 17

NFL

SPREAD

TO WIN

TOTAL

New York Jets

NYJ

-3.5

-192

O 41.5

Tennessee Titans

TEN

+3.5

+157

U 41.5

SAN FRANCISCO 49ERS @ MINNESOTA VIKINGS (1 p.m., CBS)

Point spread: 49ers -4.5 (49ers favored to win by more than 4.5 points, otherwise Vikings cover)
Moneyline: 49ers -218 favorites to win (bet $10 to win $14.59 total); Vikings +180 underdogs to win (bet $10 to win $28 total)
Total scoring Over/Under: 46.5 points scored by both teams combined

FINAL

SF 17 · MIN 23

NFL

SPREAD

TO WIN

TOTAL

San Francisco 49ers

SF

-4.0

-213

O 46.5

Minnesota Vikings

MIN

+4.0

+176

U 46.5

SEATTLE SEAHAWKS @ NEW ENGLAND PATRIOTS (1 p.m., FOX and FOX Sports app)

Point spread: Seahawks -3.5 (Seahawks favored to win by more than 3.5 points, otherwise Patriots cover)
Moneyline: Seahawks -170 favorites to win (bet $10 to win $15.88 total); Patriots +142 underdogs to win (bet $10 to win $24.20 total)
Total scoring Over/Under: 38 points scored by both teams combined

FINAL / OT

SEA 23 · NE 20

NFL

SPREAD

TO WIN

TOTAL

Seattle Seahawks

SEA

-3.0

-165

O 39

New England Patriots

NE

+3.0

+140

U 39

NEW YORK GIANTS @ WASHINGTON COMMANDERS (1 p.m., FOX and FOX Sports app)

Point spread: Commanders -1.5 (Commanders favored to win by more than 1.5 points, otherwise Giants cover)
Moneyline: Commanders -122 favorites to win (bet $10 to win $18.20 total); Giants +102 underdogs to win (bet $10 to win $20.20 total)
Total scoring Over/Under: 43.5 points scored by both teams combined

FINAL

NYG 18 · WAS 21

NFL

SPREAD

TO WIN

TOTAL

New York Giants

NYG

+1.5

+105

O 43

Washington Commanders

WAS

-1.5

-124

U 43

LOS ANGELES CHARGERS @ CAROLINA PANTHERS (1 p.m., CBS)

Point spread: Chargers -5.5 (Chargers favored to win by more than 5.5 points, otherwise Panthers cover)
Moneyline: Chargers -225 favorites to win (bet $10 to win $14.44 total); Panthers +185 underdogs to win (bet $10 to win $28.50 total)
Total scoring Over/Under: 39 points scored by both teams combined

FINAL

LAC 26 · CAR 3

NFL

SPREAD

TO WIN

TOTAL

Los Angeles Chargers

LAC

-4.5

-223

O 39

Carolina Panthers

CAR

+4.5

+184

U 39

CLEVELAND BROWNS @ JACKSONVILLE JAGUARS (1 p.m., CBS)

Point spread: Jaguars -3 (Jaguars favored to win by more than 3 points, otherwise Browns cover)
Moneyline: Jaguars -175 favorites to win (bet $10 to win $15.71 total); Browns +145 underdogs to win (bet $10 to win $24.50 total)
Total scoring Over/Under: 41.5 points scored by both teams combined

FINAL

CLE 18 · JAX 13

NFL

SPREAD

TO WIN

TOTAL

Cleveland Browns

CLE

+3.0

+141

O 41

Jacksonville Jaguars

JAX

-3.0

-167

U 41

LAS VEGAS RAIDERS @ BALTIMORE RAVENS (1 p.m., CBS)

Point spread: Ravens -8.5 (Ravens favored to win by more than 8.5 points, otherwise Raiders cover)
Moneyline: Ravens -395 favorites to win (bet $10 to win $12.53 total); Raiders +310 underdogs to win (bet $10 to win $41 total)
Total scoring Over/Under: 41 points scored by both teams combined

FINAL

LV 26 · BAL 23

NFL

SPREAD

TO WIN

TOTAL

Las Vegas Raiders

LV

+8.5

+344

O 42.5

Baltimore Ravens

BAL

-8.5

-444

U 42.5

LOS ANGELES RAMS @ ARIZONA CARDINALS (4:05 p.m., FOX and FOX Sports app)

Point spread: Rams -1 (Rams favored to win by more than 1 point, otherwise Cardinals cover)
Moneyline: Rams -112 favorites to win (bet $10 to win $18.93 total); Cardinals -108 underdogs to win (bet $10 to win $19.26 total)
Total scoring Over/Under: 48 points scored by both teams combined

FINAL

LAR 10 · ARI 41

NFL

SPREAD

TO WIN

TOTAL

Los Angeles Rams

LAR

-1.0

-110

O 47.5

Arizona Cardinals

ARI

+1.0

-110

U 47.5

PITTSBURGH STEELERS @ DENVER BRONCOS (4:25 p.m., CBS)

Point spread: Steelers -2.5 (Steelers favored to win by more than 2.5 points, otherwise Broncos cover)
Moneyline: Steelers -155 favorites to win (bet $10 to win $16.45 total); Broncos +130 underdogs to win (bet $10 to win $17.69 total)
Total scoring Over/Under: 36.5 points scored by both teams combined

FINAL

PIT 13 · DEN 6

NFL

SPREAD

TO WIN

TOTAL

Pittsburgh Steelers

PIT

-2.5

-158

O 36.5

Denver Broncos

DEN

+2.5

+129

U 36.5

CINCINNATI BENGALS @ KANSAS CITY CHIEFS (4:25 p.m., CBS)

Point spread: Chiefs -6.5 (Chiefs favored to win by more than 6.5 points, otherwise Bengals cover)
Moneyline: Chiefs -285 favorites to win (bet $10 to win $13.51 total); Bengals +230 underdogs to win (bet $10 to win $33 total)
Total scoring Over/Under: 48 points scored by both teams combined

FINAL

CIN 25 · KC 26

NFL

SPREAD

TO WIN

TOTAL

Cincinnati Bengals

CIN

+6.5

+235

O 47.5

Kansas City Chiefs

KC

-6.5

-295

U 47.5

CHICAGO BEARS @ HOUSTON TEXANS (8:20 p.m., NBC/Peacock)

Point spread: Texans -6 (Texans favored to win by more than 6 points, otherwise Bears cover)
Moneyline: Texans -245 favorites to win (bet $10 to win $14.08 total); Bears +200 underdogs to win (bet $10 to win $30 total)
Total scoring Over/Under: 45 points scored by both teams combined

FINAL

CHI 13 · HOU 19

NFL

SPREAD

TO WIN

TOTAL

Chicago Bears

CHI

+6.5

+232

O 45.5

Houston Texans

HOU

-6.5

-284

U 45.5

MONDAY, SEPT. 16

ATLANTA FALCONS @ PHILADELPHIA EAGLES (8:15 p.m., ESPN)

Point spread: Eagles -6 (Eagles favored to win by 6 points or more, otherwise Falcons cover)
Moneyline: Eagles -265 favorites to win (bet $10 to win $13.77 total); Falcons +215 underdogs to win (bet $10 to win $31.50 total)
Total scoring Over/Under: 46.5 points scored by both teams combined

FINAL

ATL 22 · PHI 21

NFL

SPREAD

TO WIN

TOTAL

Atlanta Falcons

ATL

+5.5

+205

O 46.5

Philadelphia Eagles

PHI

-5.5

-251

U 46.5

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