National Football League

2024-25 NFC West Division odds: 49ers aim for third straight title

Updated Aug. 29, 2024 12:18 p.m. ET

As expected, the reigning NFC West champion 49ers are once again projected to claim the division title this season.

San Francisco is coming off its second consecutive division title and looking to make it a 3-peat.

Over the last two seasons, the 49ers have a record of 11-1 against NFC West opponents, and the odds lean toward San Francisco doing it again.

Let's take a look at the odds at DraftKings Sportsbook as of Aug. 29.

NFC WEST DIVISION WINNER ODDS

49ers: -195 (bet $10 to win $15.13 total)
Rams: +350 (bet $10 to win $45 total)
Seahawks: +650 (bet $10 to win $75 total)
Cardinals: +1300 (bet $10 to win $140 total)

The Niners' one loss in the division came at the hands of the Rams in Week 18 of last season.

Let's take a look at the key points to know regarding each NFC West squad.

SAN FRANCISCO 49ERS

2023-24 division finish: 1st (5-1)

Bottom line: The Niners have made the Super Bowl twice in the past five years and lost to the Chiefs both times. The assumption would be that they have bigger fish to fry outside of winning their division, which they've done twice in a row and three times in the past five seasons. The question is, who can challenge San Francisco, winners of 11 of its last 12 NFC West games?

LOS ANGELES RAMS

2023-24 division finish: 2nd (5-1)

Bottom line: The Rams figure to be San Francisco's greatest challenge in the division, as the last team to defeat S.F. in a division game and as the only other playoff team from the NFC West last season. L.A. also finished 5-1 in the division last season but lost the tiebreaker to S.F. via overall record. The Rams still have their quarterback in Matthew Stafford and a star receiving corps.

Rams dethrone 49ers for NFC West crown in Nick Wright's predictions

SEATTLE SEAHAWKS

2023-24 division finish: 3rd (2-4)

Bottom line: Seattle has a new head coach and appears to be on the way to running it back with Geno Smith. In 35 starts for the Seahawks over the last three seasons, Smith has gone 18-17. Seattle finished 2-4 in the division last season, with its two wins coming against the lowly Cardinals, who finished 4-13 overall.

ARIZONA CARDINALS

2023-24 division finish: 4th (0-6)

Bottom line: Arizona figures to be the wild card in the division next season, with starting QB Kyler Murray firmly back in the fold after missing nine games last season recovering from a torn ACL. He went 3-5 in eight starts last season but suffered division losses to the Rams, Seahawks and Niners. Arizona last won the division in 2015. A win or two in-division could shake things up for the teams up top.

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