National Football League

NFL odds Week 1: Lines for every game, picks, results

Updated Sep. 13, 2022 12:21 p.m. ET

How did you fare on your wagers for Week 1 of the NFL season? You're celebrating if you bet on the Colts-Texans ending in a tie!

Here is everything you need to know about the NFL odds for Week 1 — the point spread, moneyline, total over/under for every game, results and picks by FOX Sports betting analyst Jason McIntyre (with all NFL odds via FOX Bet).

Can Dak Prescott lead this year's Cowboys to a Super Bowl? | UNDISPUTED

The Cowboys have sky-high expectations and it all comes down to Dak.

From gambling-friendly schedules featuring live, updating odds to expert analysis and the day's most-bet games, check out the all-new "NFL Odds" section on the FOX Sports App and FOXSports.com!

The defending Super Bowl champion Los Angeles Rams and 2021 Offensive Player of the Year, wide receiver Cooper Kupp, opened the season by taking an L to quarterback Josh Allen and the Super Bowl favorites, the Buffalo Bills. Will the remaining nine home underdogs fare any better?

Tom Brady and the Tampa Bay Buccaneers finished off Sunday's slate of games by beating the Dallas Cowboys.

Week 1 wraps up with the Denver Broncos and new quarterback Russell Wilson traveling to Seattle to take on Wilson's former team, the Seahawks, on Monday Night Football.

Here are the updated Week 1 lines and betting results for every game (via FOX Bet):

COMPLETED GAMES

Seattle Seahawks 17, Denver Broncos 16

Point spread: Seahawks (+7) cover by winning outright
Moneyline: Seahawks win as +240 underdogs (bet $10 to win $32.50 total); Broncos were -333 favorites (bet $10 to win $13.33 total)
Total scoring over/under: Under 44.5 points scored by both teams combined (33)

RELATED: How to Bet Broncos-Seahawks

Tampa Bay Buccaneers 19, Dallas Cowboys 3

Point spread: Buccaneers (-2.5) covered by winning by more than 2.5 points (16)
Moneyline: Buccaneers win as -143 favorites (bet $10 to win $16.99 total); Cowboys were +110 underdogs (bet $10 to win $21 total)
Total scoring over/under: Under 50 points scored by both teams combined (22)

RELATED: How to Bet Buccaneers-Cowboys

New York Giants 21, Tennessee Titans 20

Point spread: Giants (+5.5) cover by winning outright
Moneyline: Giants win as +205 underdogs (bet $10 to win $30.50 total); Titans were -278 favorites (bet $10 to win $13.60 total)
Total scoring over/under: Under 44 points scored by both teams combined (41)

RELATED: How to Bet Giants-Titans

NOTES: Saquon Barkley caught a 2-yard shovel pass from Daniel Jones for a two-point conversion with 1:06 remaining for New York. … The Giants held on for the win when Tennessee's Randy Bullock was wide left on a 47-yard field-goal attempt with four seconds to go.

McIntyre: "I’m not a trend bettor, but one worth looking at in Week 1: Teams that didn’t make the playoffs last season against teams that did. Like it or not, the prior year’s playoff team tends to be overvalued in the market.

"When it comes to this matchup, the Titans were the No. 1 seed in the AFC last year. On the flip side, the Giants were one of the league’s biggest dumpster fires, and they fired their coach.

"I like New York’s new coach, Brian Daboll, and think he will be a tremendous value add to struggling QB Daniel Jones. The Giants will be undervalued with a full arsenal of healthy weapons — like Saquon Barkley and Kenny Golladay — in September.

"Getting nearly a touchdown in this spot is too good to pass up."

PICK: Giants (+6.5 at FOX Bet at time of pick) to lose by fewer than 6.5 points (or win outright) WIN

Minnesota Vikings 23, Green Bay Packers 7

Point spread: Vikings (-1.5) cover by winning by more than 1.5 points (16)
Moneyline: Vikings win as -138 favorites (bet $10 to win $17.25 total); Packers were +110 underdogs (bet $10 to win $22 total)
Total scoring over/under: Under 46.5 points scored by both teams combined (30)

RELATED: How to Bet Packers-Vikings

Kansas City Chiefs 44, Arizona Cardinals 21

Point spread: Chiefs (-6) cover by winning by more than 6 points (23)
Moneyline: Chiefs win as -278 favorites (bet $10 to win $13.60 total); Cardinals were +205 underdogs (bet $10 to win $30.50 total)
Total scoring over/under: Over 53.5 points scored by both teams combined (65)

RELATED: How to Bet Chiefs-Cardinals

Los Angeles Chargers 24, Las Vegas Raiders 19

Point spread: Chargers (-3.5) cover by winning by more than 3.5 points, (5)
Moneyline: Chargers win as -182 favorites (bet $10 to win $15.49 total); Raiders were +140 underdogs (bet $10 to win $24 total)
Total scoring over/under: Under 52.5 points scored by both teams combined (43)

RELATED: How to Bet Raiders-Chargers

Pittsburgh Steelers 23, Cincinnati Bengals 20 (OT)

Point spread: Steelers (+7) cover by winning outright
Moneyline: Steelers win as +240 underdogs (bet $10 to win $34 total); Bengals were -333 favorites (bet $10 to win $13 total)
Total scoring over/under: Under 44.5 points scored by both teams combined (43)

NOTES: The Bengals tied the game with 2 seconds left in the fourth quarter on Ja'Marr Chase's touchdown catch but Pittsburgh's Minkah Fitzpatrick, who had a pick six on Cincinnati's first drive, blocked the extra point to force overtime. … Both teams missed field-goal attempts in OT. Cincinnati's Evan McPherson was wide left on a 29-yard attempt with 3:37 remaining. Pittsburgh's Chris Boswell hit the left upright from 55 yards with 2:27 to go but made the winning kick from 53 yards as time expired.

FOX Bet's Jason McIntyre: "Mike Tomlin as an underdog in a division game? Take my money. The Bengals will be the most overvalued team in the market next season. Yes, they have an elite QB/WR combo in Joe Burrow and Ja’Marr Chase, but let’s also remember this team faced the third-easiest schedule in the NFL last season.

"The Bengals will now face the seventh-most difficult schedule when looking at the opponent's season win totals. Bengals fans can earmuff the rest; everyone else, listen closely. Cincinnati held on to beat the Raiders when they failed inside the 10-yard line on fourth down. The Bengals beat the Titans on a walk-off field goal and then beat the Chiefs in overtime despite KC getting the ball first. If they don’t win all three of those games, Pittsburgh is probably closer to +3 or +3.5.

"This line is inflated. Give me the extra points."

PICK: Steelers (+7) to lose by fewer than 7 points (or win outright) WIN

Cleveland Browns 26, Carolina Panthers 24

Point spread: Browns (+2) cover by winning outright
Moneyline: Browns win as +100 underdogs (bet $10 to win $20 total); Panthers were -125 favorites (bet $10 to win $18 total);
Total scoring over/under: Over 42 points scored by both teams combined (50)

RELATED: How to Bet Browns-Panthers

NOTES: Cade York's 58-yard field goal with 8 seconds left in his NFL debut lifted Cleveland over Carolina. … The Browns are 1-0 for the first time since 2004.

New Orleans Saints 27, Atlanta Falcons 26

Point spread: Saints -5.5 (Saints favored to win by more than 5.5 points, otherwise Falcons cover)
Moneyline: Saints -250 favorites to win (bet $10 to win $14 total); Falcons +190 underdogs to win (bet $10 to win $29 total)
Total scoring over/under: 43.5 points scored by both teams combined

RELATED: How to Bet Saints-Falcons

NOTES: Will Lutz's 51-yard field goal with 19 seconds to go helped New Orleans rally from a 16-point deficit in the fourth quarter. … Saints quarterback Jameis Winston was 13-for-16 passing (with two intentional spikes) for 212 yards and two touchdowns in the period.

Philadelphia Eagles 38, Detroit Lions 35

Point spread: Lions (+5.5) cover by losing by fewer than 5.5 points (3)
Moneyline: Eagles win as -250 favorites (bet $10 to win $14 total); Lions were +190 underdogs (bet $10 to win $29 total)
Total scoring over/under: Over 48 points scored by both teams combined (73)

RELATED: How to Bet Eagles-Lions

Baltimore Ravens 24, New York Jets 9

Point spread: Ravens (-6.5) covers by winning by more than 6.5 points (15)
Moneyline: Ravens win as -303 favorites (bet $10 to win $13.30 total); Jets ware +220 underdogs (bet $10 to win $32 total)
Total scoring over/under: Under 44 points scored by both teams combined (33)

RELATED: How to Bet Ravens-Jets

Miami Dolphins 20, New England Patriots 7

Point spread: Dolphins (-3) cover by winning by more than 3 points (13)
Moneyline: Dolphins win as -162 favorites (bet $10 to win $16.15 total); Patriots were +125 underdogs (bet $10 to win $22.50 total)
Total scoring over/under: Under 46.5 points scored by both teams combined (27)

Chicago Bears 19, San Francisco 49ers 10

Point spread: Bears (+6.5) cover by winning outright
Moneyline: Bears were +220 underdogs (bet $10 to win $32 total); 49ers were -303 favorites (bet $10 to win $13.30 total)
Total scoring over/under: Under 37 points scored by both teams combined (29)

RELATED: How to Bet 49ers-Bears

Jacksonville Jaguars 28, Washington Commanders 22

Point spread: Commanders (-3) cover by winning by more than 3 points (6)
Moneyline: Commanders win as -162 favorites (bet $10 to win $16.17 total); Jaguars were +125 underdogs (bet $10 to win $22.50 total)
Total scoring over/under: Over 43.5 points scored by both teams combined (50)

Indianapolis Colts 20, Houston Texans 20 (OT)

Point spread: Texans (+7) cover by playing to a tie
Moneyline: Colts were -400 favorites (bet $10 to win $12.50 total); Texans were +280 underdogs (bet $10 to win $38 total)
Total scoring over/under: Under 46 points scored by both teams combined (40)

RELATED: How to Bet Colts-Texans

Buffalo Bills 31, Los Angeles Rams 10

Point spread: Bills (-2) cover by winning by more than 2 points (21)
Moneyline: Bills win as -138 favorites (bet $10 to win $17.25 total); Rams were +115 underdogs (bet $10 to win $21.50 total)
Total scoring over/under: Under 52 points scored by both teams combined (41)

If you are betting on this week's NFL slate, check out these posts below because we have you covered from every possible angle!

— Warren Sharp gives you his sharpest betting edges for Week 1

— Our Insider Patrick Everson breaks down all the hot, big -money chatter from Las Vegas

— This week's card features a record number of home underdogs. Read which dogs Jason McIntyre thinks have a chance to bark.

— Geoff Schwartz's best wagers

— Jason McIntyre's favorite bets

— Sammy P's sharp college football and NFL wagers

— Our experts' Super Bowl picks

Looking for even more NFL content? Head over to the NFL section on the FOX Sports app and website for all the latest news, and make sure to favorite the NFL and your favorite team — or teams! — while you're there.