College Football

College Football Week 6 Opening Odds

Updated Mar. 4, 2020 9:17 p.m. ET

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Special to Outkick The Coverage from OddsShark.com

Ohio State is a 28.5-point favorite on the opening Week 6 betting lines at sportsbooks monitored by OddsShark.com for their home game against Maryland on Saturday, one week after they got past Indiana 34-27 on the road but failed to cover the 21.5-point spread.

That means Ohio State is 5-0 straight up but 1-4 against the spread so far this season, and they head into Saturday's game at 0-5 ATS in their last five games at home according to the OddsShark College Football Database. Maryland, though, is 2-5 both SU and ATS in its last seven games.

Also on Saturday, the Oklahoma Sooners are 13.5-point favorites against the Texas Longhorns for their annual Red River Rivalry clash at the Cotton Bowl. Oklahoma beat Texas 31-26 but failed to cover the 16.5-point spread in this matchup last year. The Longhorns are 1-6 both SU and ATS in their last seven games, and they were blasted 50-7 by TCU as a 14.5-point underdog on the weekend.

Elsewhere, Notre Dame opened as a 16-point home favorite against Navy for Saturday at the sportsbooks, with the OVER having paid off for totals bettors in each of their last five matchups. Clemson opened as a 7.5-point home favorite against Georgia Tech, Utah opened as a 7-point home favorite against California, and Michigan State opened as a 17-point road favorite against Rutgers.

Check out the opening college football odds for the week. Live odds and matchup reports on every game every day, head over to the OddsShark.com college football betting section.

SMU at Houston -21 (THU)

Washington at USC -17 (THU)

Southern Mississippi at Marshall -6.5 (FRI)

NC State at Virginia Tech -2 (FRI)

Duke at Army +11

New Mexico State at Ole Miss -43

LSU at South Carolina +13

UTEP at Florida International -13

Middle Tennessee at Western Kentucky -7.5

Illinois at Iowa -10

Baylor at Kansas +38

Oklahoma vs Texas +13.5