Mahomes completed 23 of 33 pass attempts for 196 yards, three touchdowns and two interceptions without recording a carry in Sunday's 30-21 loss to Buffalo.
Butker is expected to return from injured reserve when first eligible Week 15 against the Browns after undergoing a meniscus trim of his left knee earlier this week, rather than a full meniscus repair, Jay Glazer of Fox Sports reports.
Pacheco (ankle) is expected to be ready to return from injured reserve for the Chiefs' Week 12 game against the Panthers, Ian Rapoport of NFL Network reports.
Coach Andy Reid said Shrader will handle all kicking duties for the Chiefs during Harrison Butker's (knee) absence, Charles Goldman of AtoZSports.com reports.
Coach Andy Reid said that Butker underwent surgery on his injured left knee Friday and doesn't have a timeline for his return to action, Jesse Newell of The Kansas City Star reports.
Coach Andy Reid said Friday that Pacheco (ankle), who remains on injured reserve, won't play Sunday at Buffalo, Sam McDowell of The Kansas City Star reports.